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Linda Scoriels


Associate professor

Paris Cité University

Linda is a researcher at LaPsyDÉ and an associate professor in cognitive neuroscience at the Institute of Psychology, Université Paris Cité. She completed a Magistère in Genetics, followed by a Master's degree in Cognitive Neuroscience in Paris between 2002 and 2005. She then completed a PhD in Neuroscience at the University of Cambridge, UK, under the supervision of Peter Jones in 2010, followed by a first postdoctorate. Then, after obtaining a ‘Young Talent’ funding from the Brazilian government, Linda moved to the Federal University of Rio de Janeiro (UFRJ), where she completed her 2nd postdoctorate, followed by a position as substitute assistant professor in the UFRJ Faculty of Medicine. On her return to Paris in 2021, she joined the Krebs team at the Psychiatry and Neurosciences Institute of Paris, where she was appointed scientific director of two multicentre clinical trials in France. She co-directed the theses of Larissa Genaro (2018), Erica Woodruff (2018), Anna-Luiza Guimarães (2022), Valeria Lucarini (ongoing), Delphine Yeh (ongoing) on the role of cognitive and emotional functions in psychosis and ageing.

Her research focuses on the biological and environmental characterisation of cognitive and emotional processes in development, psychiatric disorders and ageing. She also seeks to develop pharmacological and digital cognitive enhancement strategies for these different populations, in order to improve cognitive and emotional processes, as well as functioning and quality of life of these individuals.


Frajerman, A., Urban, M., Rivollier, F., Plaze, M., Chaumette, B., Krebs, M.-O., & Scoriels, L. (2023). Abnormalities in one-carbon metabolism in young patients with psychosis. Frontiers in Psychiatry, 14, 1128890.


Mororó, L. G., Guimarães, A. L., Costa, A. C., Genaro, L., Cavalcanti, M. T., Scoriels, L., & Panizzutti, R. (2023). Association between motivation and engagement with changes in cognition and symptoms after digital cognitive training in schizophrenia. Schizophrenia Research, 251, 1–9.

Couturier, A., Chaumette, B., Kebir, O., Iftimovici, A., Krebs, E., He, Q., Jiao, C., Krebs, M.-O., Scoriels, L., & Frajerman, A. (2022). The impact of BDNF on the cognitive functions of ultra-high risk patients: An exploratory study. Schizophrenia Research, S0920-9964(22)00432-7.

Scoriels, L., Genaro, L. T., Keffer, S., Guimarães, A. L., Barros-Dumas, B., Mororó, L. G., Biagioni, T., Lucena, C., da Hora, T. R., Sahakian, B. J., Fisher, M., Vinogradov, S., & Panizzutti, R. (2022). Changes in emotion processing and social cognition with auditory versus visual neuroscience-informed cognitive training in individuals with schizophrenia. Schizophrenia Research, 241, 267–274.

Guimarães, A. L., Richer Araujo Coelho, D., Scoriels, L., Mambrini, J., Ribeiro do Valle Antonelli, L., Henriques, P., Teixeira-Carvalho, A., Assis Martins Filho, O., Mineo, J., Bahia-Oliveira, L., & Panizzutti, R. (2022). Effects of Toxoplasma gondii infection on cognition, symptoms, and response to digital cognitive training in schizophrenia. Schizophrenia (Heidelberg, Germany), 8(1), 104.


Frajerman, A., Scoriels, L., Kebir, O., & Chaumette, B. (2021). Shared Biological Pathways between Antipsychotics and Omega-3 Fatty Acids: A Key Feature for Schizophrenia Preventive Treatment? International Journal of Molecular Sciences, 22(13), Article 13.


Genaro, L. T., Santos, P. V., Mororó, L. G. C., Panizzutti, R., & Scoriels, L. (2021). The psychometric properties of the Behavioral Inhibition and Activation Systems motivational scale and a Brazilian Portuguese validation. Learning and Motivation, 75, 101743.

Scoriels, L., Genaro, L. T., Mororó, L. G. C., Keffer, S., Luiza, A., Guimarães, D. V., Ribeiro, P. V. S., Tannos, F. M., Novaes, C., França, A. I., Goldenstein, N., Sahakian, B. J., Cavalcanti, M. T., Fisher, M., Vinogradov, S., & Panizzutti, R. (2020). Auditory versus visual neuroscience-informed cognitive training in schizophrenia: Effects on cognition, symptoms and quality of life. Schizophrenia Research, 222, 319-326.


Toll, A., Bergé, D., Burling, K., Scoriels, L., Treen, D., Monserrat, C., Marmol, F., Duran, X., Jones, P. B., Pérez-Solà, V., Fernandez-Egea, E., & Mané, A. (2020). Cannabis use influence on peripheral brain-derived neurotrophic factor levels in antipsychotic-naïve first-episode psychosis. European Archives of Psychiatry and Clinical Neuroscience, 270(7), 851–858.

Scoriels, L., Zimbron, J., Garcia-León, N., Coll-Negre, M., Giro, M., Perez, J., Jones, P. B., & Fernandez-Egea, E. (2019). Cross-sectional study of diet patterns in early and chronic schizophrenia. Schizophrenia Research, 208.

Lennox, B. R., Palmer-Cooper, E. C., Pollak, T., Hainsworth, J., Marks, J., Jacobson, L., Lang, B., Fox, H., Ferry, B., Scoriels, L., Crowley, H., Jones, P. B., Harrison, P. J., & Vincent, A. (2017). Prevalence and clinical characteristics of serum neuronal cell surface antibodies in first-episode psychosis: A case-control study. The Lancet Psychiatry, 4(1).


Lennox, B. R., Pollak, T., Palmer-Cooper, E. C., Scoriels, L., Harrison, P. J., Jones, P. B., Lang, B., Crowley, H., Marks, J., & Vincent, A. (2017). Serum neuronal cell-surface antibodies in first-episode psychosis–Authors’ reply. The Lancet Psychiatry, 4(3).

Calderon, J., Flores, P., Aguirre, J. M., Valdivia, G., Padilla, O., Barra, I., Scoriels, L., Herrera, S., Gonzalez, A., & Massardo, L. (2016). Impact of cognitive impairment, depression, disease activity, and disease damage on quality of life in women with systemic lupus erythematosus. Scandinavian Journal of Rheumatology, 1–8.

Scoriels, L., Avellar, M., Madeira, C., Vargas-Lopes, C., Marques, P., Dantas, C., Manhães, A. C., Leite, H., & Panizzutti, R. (2016). The effect of D-serine administration on cognition and mood in older adults. Oncotarget, 7(11).


Xu, M. K., Gaysina, D., Barnett, J. H., Scoriels, L., van de Lagemaat, L. N., Wong, a, Richards, M., Croudace, T. J., & Jones, P. B. (2015). Psychometric precision in phenotype definition is a useful step in molecular genetic investigation of psychiatric disorders. Translational Psychiatry, 5(6), e593–e593.


Scoriels, L., Salek, R. M., Goodby, E., Grainger, D., Dean, a M., West, J. a, Griffin, J. L., Suckling, J., Nathan, P. J., Lennox, B. R., Murray, G. K., Bullmore, E. T., & Jones, P. B. (2015). Behavioural and molecular endophenotypes in psychotic disorders reveal heritable abnormalities in glutamatergic neurotransmission. Translational Psychiatry, 5(January), e540–e540.


Massardo, L., Bravo-Zehnder, M., Calderón, J., Flores, P., Padilla, O., Aguirre, J. M., Scoriels, L., & González, a. (2015). Anti-N-methyl-D-aspartate receptor and anti-ribosomal-P autoantibodies contribute to cognitive dysfunction in systemic lupus erythematosus. Lupus, 24(6), 558–568.

Panizzutti, R., Scoriels, L., & Avellar, M. (2014). The co-agonist Site of NMDA-glutamate receptors: A novel therapeutic target for age-related cognitive decline. Curr Pharm Des, 20(32), 5160–5168.

Zandi, M. S., Deakin, J. B., Morris, K., Buckley, C., Jacobson, L., Scoriels, L., Cox, A. L., Coles, A. J., Jones, P. B., Vincent, A., & Lennox, B. R. (2014). Immunotherapy for patients with acute psychosis and serum N-Methyl d-Aspartate receptor (NMDAR) antibodies: A description of a treated case series. Schizophrenia Research, 160(1–3).

Calderón, J., Flores, P., Babul, M., Aguirre, J., Slachevsky, a, Padilla, O., Scoriels, L., Henríquez, C., Cárcamo, C., Bravo-Zehnder, M., González, a, & Massardo, L. (2014). Systemic lupus erythematosus impairs memory cognitive tests not affected by depression. Lupus, 2014, 1042–1053.

Fernandez-Egea, E., Scoriels, L., Theegala, S., Giro, M., Ozanne, S. E., Burling, K., & Jones, P. B. (2013). Cannabis use is associated with increased CCL11 plasma levels in young healthy volunteers. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 46, 25–28.

Dean, a M., Goodby, E., Ooi, C., Nathan, P. J., Lennox, B. R., Scoriels, L., Shabbir, S., Suckling, J., Jones, P. B., Bullmore, E. T., & Barnes, A. (2013). Speed of facial affect intensity recognition as an endophenotype of first-episode psychosis and associated limbic-cortical grey matter systems. Psychological Medicine, 43(3), 591–602.

Scoriels, L., Jones, P. B., & Sahakian, B. J. (2013). Modafinil effects on cognition and emotion in schizophrenia and its neurochemical modulation in the brain. Neuropharmacology, 64, 168–184.

Scoriels, L., Barnett, J. H., Soma, P. K., Sahakian, B. J., & Jones, P. B. (2012). Effects of modafinil on cognitive functions in first episode psychosis. Psychopharmacology, 220(2), 249–258.

Barnett, J. H., Scoriels, L., & Munaf, M. R. (2011). Reply to: With great power comes great responsibility: Meta-analytic proof for a timeless insight. Biological Psychiatry, 69(10).

Scoriels, L., Barnett, J. H., Murray, G. K., Cherukuru, S., Fielding, M., Cheng, F., Lennox, B. R., Sahakian, B. J., & Jones, P. B. (2011). Effects of modafinil on emotional processing in first episode psychosis. Biological Psychiatry, 69(5), 457–464.

Scoriels, L., Barnett, J., & Jones Peter, B. (2010). Modafinil for schizophrenia. Cochrane Database of Systematic Reviews, 9.

Kirkbride, J. B., & Scoriels, L. (2009). Review of the 6th symposium for the search for the causes of schizophrenia, Sao Paulo, Brazil, 3-6 February 2009. European Archives of Psychiatry and Clinical Neuroscience, 259(8), 505–509.

Barnett, J. H., Scoriels, L., & Munafò, M. R. (2008). Meta-Analysis of the Cognitive Effects of the Catechol-O-Methyltransferase Gene Val158/108Met Polymorphism. Biological Psychiatry, 64(2), 137–144.

Mechawar, N., Saghatelyan, A., Grailhe, R., Scoriels, L., Gheusi, G., Gabellec, M.-M., Lledo, P.-M., & Changeux, J.-P. (2004). Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proceedings of the National Academy of Sciences of the United States of America, 101(26), 9822–9826.

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