Elise Klein

MD, Ph.D

Chargée de recherche

CNRS

Elise est chercheure CNRS à l’Université de Paris depuis 2020. Elle est une neuroscientifique cognitive ayant à la fois une formation médicale (MD) et en psychologie (PhD). Ses recherches, à l'intersection des neurosciences cognitives, de la (neuro)psychologie expérimentale et de la psychologie du développement, sont consacrées à la compréhension des fondements cognitifs et neuronaux de la cognition numérique.
Après avoir obtenu son diplôme de médecine (Université RWTH d'Aix-la-Chapelle, Allemagne) en 2007, Elise a obtenu son diplôme de docteur en médecine à l'Université RWTH d'Aix-la-Chapelle en 2009 (summa cum laude, superviseur : Klaus Willmes) et son doctorat à l'Université de Tübingen (Allemagne) en 2012 (summa cum laude, superviseur : Hans-Christoph Nuerk). Elle a été chercheure post-doctorale au laboratoire de Korbinian Moeller à l'Institut Leibniz (IWM) de Tuebingen (Allemagne) de 2012 à 2019, où elle a dirigé le groupe de recherche junior NeuroLearn de 2014 à 2019. Elle a également obtenu une bourse Wrangell-Fellowship (2015-2019).
Les travaux d'Elise reposent sur l'idée que les fonctions cognitives supérieures normales et altérées ne peuvent être pleinement expliquées qu'en combinant la compréhension de leurs corrélations avec la matière grise neurale et de leur connectivité structurelle et fonctionnelle avec le comportement.

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PUBLICATIONS

Jung, S., Moeller, K., Klein, E., & Heller, J. (2021). Mode effect: An issue of perspective? Writing mode differences in a spelling assessment in German children with and without developmental dyslexia. Dyslexia, 1-38. https://doi.org/10.1002/dys.1675

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Klein, E., Babai, R., Ischebeck, A. & Moeller, K. (2021). Editorial: Neuro-cognitive Architecture of Numerical Cognition and Its Development. Frontiers in Human Neuroscience, 15, 670460. https://doi.org/10.3389/fnhum.2021.670460

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Greipl, S., Klein, E., Lindstedt, A., Kiili, K., Moeller, K., Karnath, H.- O., Bahnmueller, J., Bloechle, J., & Ninaus, M. (2021). When the brain comes into play: Neurofunctional correlates of emotions and reward in game-based learning. Computers in Human Behavior, 125, 106946. https://doi.org/10.1016/j.chb.2021.106946

Kaufmann, L., von Aster, M., Goebel., S.M., Marksteiner, J. Klein, E. (2020). Developmental dyscalculia in adults: Current issues and open questions for future research. Lernen und Lernstoerungen, 9, 126-137. https://doi.org/10.1024/2235-0977/a000294

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Wortha, S.M, Bloechle, J., Ninaus, M., Kiili, K., Lindstedt, A., Bahnmueller, J., Moeller, K. Klein, E. (2020). Neurofunctional plasticity in fraction learning: an fMRI training study. Trends in Neuroscience and Education, 21, Article 100141. https://doi.org/10.1016/j.tine.2020.100141

Jung, S., Roesch, S., Klein, E., Dackermann, T., Heller, J., Moeller, K. (2020). The strategy matters: Bounded and unbounded number line estimation in secondary school children. Cognitive Development, 53, Article 100839. https://doi.org/10.1016/j.cogdev.2019.100839

Colling, L.J.*, Szűcs, D.*, De Marco, D., Cipora, K., Ulrich, R., Nuerk, HC., Soltanlou, M., Bryce, D., Chen, SC., Schroeder, PA., Henare, DT., Chrystall, CK., Corballis, PM., Ansari, D., Goffin, C., Sokolowwski, HM., Hancock, PJB., Millen, AE., Langton, SRH., ... McShane, BB.* (2020). Registered Replication Report on Fischer, Castel, Dodd, and Pratt (2003). Advances in Methods and Practices in Psychological Science, 3(2), 143-162. https://doi.org/10.1177/2515245920903079

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Jung, S., Moeller, K., Karnath, H. O., Klein, E. (2020). Hemispheric lateralization of arithmetic facts and magnitude processing for two-digit numbers. Frontiers in Human Neuroscience, 14, 88. https://doi.org/10.3389/fnhum.2020.00088

Mock, J., Huber, S., Bloechle, J., Bahnmueller, J., Moeller, K., Klein, E. (2019). Processing symbolic and non-symbolic proportions: Domain-specific numerical and domain-general processes in intraparietal cortex. Brain Research, 1714, 133-146. https://doi.org/10.1016/j.brainres.2019.02.029

Klein, E., Bieck, S.M., Bloechle, J., Huber, S., Bahnmueller, J., Willmes, K. Moeller, K. (2019). Anticipation of difficult tasks - neural correlates of negative emotions and emotion regulation. Behavioral and Brain Functions, 15(1), 4.

Klein, E., Willmes, K., Bieck, S.M., Bloechle, J., Moeller, K. (2019). White matter neuro-plasticity in mental arithmetic: changes in hippocampal connectivity following arithmetic drill training. Cortex, 114, 115-123. https://doi.org/10.1016/j.cortex.2018.05.017

Dietrich, J. F., Nuerk, H. C., Klein, E., Moeller, K., Huber, S. (2019). Set size influences the relationship between ANS acuity and math performance: a result of different strategies? Psychological Research, 83(3), 590-561.

Ninaus, M., Greipl, S., Kiili, K., Lindstedt, A., Huber, S., Klein, E., Karnath, H.-O., Moeller, K. (2019). Increased emotional engagement in game-based learning - A machine learning approach on facial emotion detection data. Computers Education, 142, 103641.

Bloechle, J., Huber, S., Klein, E., Bahnmueller, J., Moeller, K., Rennig, J. (2018). Neuro-cognitive mechanisms of global Gestalt perception in visual quantification. NeuroImage, 181, 359-369.

Mock, J., Huber, S., Bloechle, J., Dietrich, J.F., Bahnmueller, J., Rennig, J., Klein, E., Moeller, K. (2018). Magnitude processing of symbolic and non-symbolic proportions: an fMRI study. Behavioral and Brain Functions, 14(1), 9.

Bloechle, J., Huber, J., Klein, E., Bahnmueller, J., Rennig, J., Moeller, K., Huber, S. (2018). Spatial arrangement and set size influence the coding of non-symbolic quantities in the intraparietal sulcus. Frontiers in Human Neuroscience, 12, 54.

Bieck, S. M., Artemenko, C., Moeller, K., Klein, E. (2018). Low to no effect: application of tRNS during two-digit addition. Frontiers in Neuroscience, 12, 176.

Klein, E., Moeller, K., Huber, S., Willmes, K., Kiechl-Kohlendorfer, U. Kaufmann, L. (2018). Gestational age modulates neural correlates of intentional, but not automatic number magnitude processing in children born preterm. International Journal of Developmental Neuroscience, 65, 38-44.

Braga, L.W., Amemiya, E., Tauil, A., Suguieda, D., Lacerda, C., Klein, E., Dehaene-Lambertz, G., Dehaene, S. (2017). Tracking adult literacy acquisition with functional MRI: a single-case study. Mind, Brain and Education, 11, 121-132.

Bloechle, J., Huber, S., Bahnmueller, J., Rennig, J., Willmes, K., Cavdaroglu, S., Moeller, K., Klein, E. (2016). Fact Learning in Complex Arithmetic - The Role of the Angular Gyrus revisited. Human Brain Mapping, 37, 3061-3079.

Scharinger, M., Domahs, U., Klein, E. Domahs, F. (2016). Mental representations of vowel features asymmetrically modulate activity in superior temporal sulcus. Brain and Language, 163, 42-49.

Klein, E., Willmes, K., Jung, S., Huber, S., Braga, L. W., Moeller, K. (2016). Differing connectivity of Exner's area for numbers and letters. Frontiers in Human Neuroscience, 10, 281. [OA]

Huber, S., Klein, E., Moeller, K., Willmes, K. (2016). Spatial-numerical and ordinal positional associations coexist in parallel. Frontiers in Psychology, 7, 438.

Spüler, M., Walter, C., Rosenstiel, W., Gerjets, P., Moeller, K., Klein, E. (2016). EEG-based prediction of cognitive workload induced by arithmetic - A step towards online adaptation in numerical learning. ZDM Mathematics and Education, 1-12. doi:10.1007/s11858-015-0754-8.

Klein, E., Suchan, J., Moeller, K., Karnath, H.-O., Knops, A., Wood, G., Nuerk, H.-C., Willmes K. (2016). Considering structural connectivity in the triple code model of numerical cognition - Differential connectivity for magnitude processing and arithmetic facts. Brain Structure and Function, 221(2), 979-95.

Morozova, M., Koschutnig, K., Klein, E., Wood, G. (2016). Monotonic non-linear transformations as a tool to investigate age-related effects on brain white matter integrity: A Box-Cox investigation. Neuroimage, 125, 1119-30.

Mock, J., Huber, S., Klein, E., Moeller, K. (2016). Insights into numerical cognition - Considering eye-fixations in number processing and arithmetic. Psychological Research, 80, 334-359.

Dietrich, J.F., Huber, S., Klein, E., Willmes, K., Pixner, S., Moeller, K. (2016). A systematic investigation of accuracy and response time based measures used to index ANS acuity. PLoS One, 11(9), e0163076. [OA]

Huber, S., Klein, E., Graf, M., Nuerk, H.-C., Moeller, K., Willmes, K. (2015). Embodied markedness of parity? Examining handedness effects on parity judgments. Psychological Research, 79, 963-977.

Jung, S., Halm, K., Huber, W., Willmes, K., Klein, E. (2015). What letters can "learn" from Arabic digits - fMRI-controlled single case therapy study of peripheral agraphia. Brain and Language, 149, 13-26.

Huber, S., Klein, E., Moeller, K., Willmes, K. (2015). Comparing a single case to a control group - Applying linear mixed effects models to repeated measures data. Cortex, 71, 148-159.

Shikhare, S., Heim, S., Klein, E., Huber, S. Willmes, K. (2015). Processing of numerical and proportional quantifiers. Cognitive Science, 39, 1504-1536.

Dietrich, J. F., Huber, S., Moeller, K., Klein, E. (2015). The influence of math anxiety on symbolic and non-symbolic magnitude processing. Frontiers in Psychology, 6, 1621. [OA]

Mihulowicz, K., Klein, E., Nuerk, H.-O., Willmes, K., Karnath, H.-O. (2015). Spatial displacement of numbers on a vertical number line in spatial neglect. Frontiers in Human Neuroscience, 9, 240. [OA]

Moeller, K., Willmes, K., Klein, E. (2015). A review on functional and structural brain connectivity in numerical cognition. Frontiers in Human Neuroscience, 9, 227.

Artemenko, C., Moeller, K., Huber, S., Klein, E. (2015). Differential influences of unilateral tDCS over the intraparietal cortex on numerical cognition. Frontiers in Human Neuroscience, 9, 110. [OA]

Rath, D., Domahs, F., Dressel, K., Claros-Salinas, D., Klein, E., Willmes, K., Krinzinger, H. (2015). Patterns of linguistic and numerical performance in aphasia. Behavioral and Brain Functions, 11:2. [OA]

Huber, S., Bahnmueller, J., Klein, E., Moeller, K. (2015). Testing a model of componential processing of multi-symbol numbers - Evidence from measurement units. Psychonomic Bulletin Review, 22, 1417-1423.

Mihulowicz, U., Willmes, K., Karnath, H.-O., Klein, E. (2014). Single-digit arithmetic processing - anatomical evidence from statistical voxel-based lesion analysis. Frontiers in Human Neuroscience, 8, 286.

Moeller, K., Klein, E., Kucian, K., Willmes, K. (2014). Numerical Development - From cognitive functions to neural underpinnings. Frontiers in Psychology, 5, 1047.

Klein, E., Moeller., K., Kiechl-Kohlendorfer, U., Kremser, C., Starke, M., Cohen Kadosh, R., Pupp-Peglow, U., Schocke, M., Kaufmann, L. (2014). Processing of intentional and automatic number magnitudes in children born prematurely - Evidence from fMRI. Developmental Neuropsychology, 39(5), 342-364.

Klein, E., Huber, S., Nuerk, H.-C., Moeller, K.(2014). Operational momentum affects eye fixation behaviour. Quarterly Journal of Experimental Psychology, 67(8), 1614-1625.

Heisterueber, M., Klein, E., Willmes, K., Heim, S., Domahs, F. (2014). Processing word prosody - behavioral and neuroimaging evidence for heterogeneous performance in a language with variable stress. Frontiers in Psychology, 5, 365.

Willmes, K., Moeller, K., Klein, E. (2014). Where numbers meet words - A common ventral network for semantic classification. Scandinavian Journal of Psychology, 55, 202-211.

Huber, S., Klein, E., Willmes, K., Nuerk, H.-C., Moeller, K. (2014). Decimal fraction representations are not distinct from natural number representations - Evidence from a combined eye-tracking and computational modelling approach. Frontiers in Human Neuroscience, 8, 172.

Ochtrup, M.-T., Rath, D., Klein, E., Krinzinger, H., Willmes, K. Domahs, F. (2013). Are Number Words Fundamentally Different? A Qualitative Analysis of Aphasic Errors in Word and Number Word Production. International Journal of Speech Language Pathology and Audiology, 1, 12-28.

Heisterüber, M., Schäffner, S., Heim, S., Klein, E., Willmes, K., Domahs, F. (2013). Funktionelle Bildgebung subklinischer Defizite in der Wortakzentverarbeitung [Neuroimaging Studies of Subclinical Deficits in Word Stress Processing]. Sprache, Stimme, Gehör, 37(1), 21-23.

Klein, E., Moeller, K., Glauche, V., Weiller, C., Willmes, K. (2013). Processing pathways in mental arithmetic - Evidence from probabilistic fiber tracking. PLoS ONE, 8(1), e55455. [OA]

Klein, E., Mann, A., Huber, S., Bloechle, J., Willmes, K., Karim, A.A., Nuerk, H.-C., Moeller, K. (2013). Bilateral bi-cephalic tDCS with two active electrodes of the same polarity modulates bilateral cognitive processes differentially. PLoS ONE, 8(8), e71607.

Klein, E., Moeller, K., Willmes, K.(2013).A neural disconnection hypothesis on impaired numerical processing. Frontiers in Human Neuroscience, 7, 663. [OA]

Klein, E., Moeller, K., Zinsberger, D., Zauner, H., Wood, G., Willmes, K., Haider, C., Gassner, A., Nuerk, H.-C. (2013). Object-based neglect in number processing. Behavioral and Brain Functions, 9, 5. [OA]

Domahs, U., Klein, E., Huber, W., Domahs, F. (2013). Good, bad and ugly word stress - fMRI evidence for foot structure driven processing of prosodic violations. Brain and Language, 125(3), 272-282.

Moeller, K., Klein, E., Nuerk, H.-C. (2013). Influences of cognitive control in numerical cognition - Adaptation by binding for implicit learning. Topics in Cognitive Science, 5(2), 335-353.

Klein, E., Bahnmueller, J., Mann, A., Pixner, S., Kaufmann, L., Nuerk, H.-C. Moeller, K. (2013). Language influences on numerical development - Inversion effects on multi-digit number processing. Frontiers in Psychology, 4, 480.

Moeller, K., Klein, E., Willmes, K., Nuerk, H.-C. (2013). Magnitude representation in sequential comparison of two-digit numbers is not holistic either. Cognitive Processing, 14, 51-62.

Domahs, F., Klein, E., Moeller, K., Nuerk, H.-C., Yoon, B.-C., Willmes, K. (2012). Multimodal semantic quantity representations Further evidence from Korean Sign Language. Frontiers in Psychology, 2, 389.

Moeller, K., Klein, E., Nuerk, H.-C., Cohen Kadosh, R. (2012). A unitary or multiple representations of numerical magnitude? - The case of symbolic and non-symbolic two-digit quantities. Frontiers in Psychology, 3, 191.

Klein, E., Domahs, U, Grande, M., Domahs, F. (2011). Neuro-cognitive foundations of word stress processing - evidence from fMRI. Behavioral and Brain Functions, 7, 15.

Moeller, K., Klein, E., Nuerk, H.-C. (2011). Three processes underlying the carry effect in addition - Evidence from eye-tracking. British Journal of Psychology, 102, 623-645.

Moeller, K., Klein, E., Nuerk, H.-C. (2011). (No) small adults - Children's processing of carry addition problems. Developmental Neuropsychology, 36(6), 702-720.

Moeller K., Klein, E., Fischer, M. H., Nuerk, H.-C., Willmes, K. (2011). Representation of Multiplication Facts - Evidence for partial verbal coding. Behavioral and Brain Functions, 7, 25. [OA]

Nuerk, H.-C., Moeller, K., Klein, E., Willmes, K., Fischer, M. H. (2011). Extending the Mental Number Line - A Review of Multi-Digit Number Processing. Journal of Psychology, 219, 3-22.

Domahs, F., Rath, D., Klein, E., Krinzinger, H. Willmes, K. (2011). Numerische und sprachliche Kognition bei Patienten mit Aphasie. Zeitschrift für Neuropsychologie, 3, 199-200.

Klein, E., Moeller, K., Willmes, K., Nuerk, H.-C., Domahs, F. (2011). The influence of implicit hand-based representations on mental arithmetic. Frontiers in Psychology, 2, 197. [OA]

Klein, E., Moeller, K., Nuerk, H.-C., Willmes K. (2010). On the neuro-cognitive foundations of basic auditory number processing. Behavioral and Brain Functions, 6, 42.

Klein, E., Willmes, K., Dressel, K., Domahs, F., Wood, G., Nuerk, H.-C., Moeller, K. (2010). Categorical and continuous - Disentangling the neural correlates of the carry effect in multi-digit addition. Behavioral and Brain Functions, 6:70.

Klein, E., Moeller, K., Dressel, K., Domahs, F., Wood, G., Willmes, K., Nuerk, H.-C. (2010). To carry or not to carry - is this the question? Disentangling the carry effect in multi-digit addition. Acta Psychologica, 135, 67-76.

Zaunmüller, L., Domahs, F., Dressel, K., Lonnemann, J., Klein, E., Ischebeck, A., Willmes, K. (2009). Rehabilitation of arithmetic fact retrieval via extensive practice A combined fMRI and behavioural case-study. Neuropsychological Rehabilitation, 19, 422-443.

Klein, E., Nuerk, H.-C., Wood, G., Knops, A., Willmes, K. (2009). The exact vs. approximate distinction in numerical cognition may not be exact, but only approximate - How different processes work together in multi-digit addition. Brain and Cognition, 2, 369-381.

Moeller, K., Pixner, S., Klein, E., Cress, U., Nuerk, H.-C. (2009). Zahlenverarbeitung ist nicht gleich Rechnen - Eine Beschreibung basisnumerischer Repräsentationen und spezifischer Interventionsansätze. Prävention und Rehabilitation, 21(3), 121-136.